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. 2002 Dec;66(4):630–670. doi: 10.1128/MMBR.66.4.630-670.2002

FIG. 11.

FIG. 11.

Telomere maintenance by recombination in the absence of telomerase. In the absence of telomerase, telomeres become progressively shorter and are maintained by RAD52-dependent recombination. Two types of recombination events give rise to survivors: RAD51-, RAD54-, and RAD57-dependent recombination between Y′ sequences, and RAD50- and RAD59-dependent recombination between T G1-3 tracts. Y′ elements are marked by open boxes, and tracts of TG1-3 are indicated by shaded boxes.

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