TABLE 1.
Potential antigenic targets selected in silico
| Class | Accession no. | Functional categorya | Function | Mr |
|---|---|---|---|---|
| I | ML0008 | 8 | Unknown | 13,722.5 |
| ML0126 | 8 | Unknown | 30,831.8 | |
| ML0678 | 8 | Unknown | 19,767.5 | |
| ML0757 | 8 | Unknown | 24,909.2 | |
| ML0957 | 8 | Unknown | 13,939.6 | |
| ML1057 | 8 | Unknown | 12,207.9 | |
| ML1420 | 8 | Unknown | 13,138.9 | |
| ML1603 | 8 | Unknown | 9,376.0 | |
| ML1829 | 8 | Unknown | 13,334.3 | |
| ML1915 | 8 | Unknown | 12,433.0 | |
| ML1979 | 8 | Unknown | 14,233.5 | |
| ML2244 | 8 | Unknown | 12,552.1 | |
| ML2249 | 8 | Unknown | 11,200.5 | |
| ML2252 | 8 | Unknown | 8,720.8 | |
| ML2264 | 8 | Unknown | 22,683.5 | |
| ML2283 | 8 | Unknown | 11,758.5 | |
| ML2567 | 8 | Unknown | 17,051.2 | |
| II | ML0308 | 10 | Conserved hypothetical protein | 25,899.1 |
| ML0333 | 10 | Conserved hypothetical protein | 26,453.1 | |
| ML0336 | 3 | ABC transporter ATP-binding protein | 30,185.6 | |
| ML0394 | 7 | Methyltransferase | 19,170.1 | |
| ML0397 | 3 | Transporter | 63,963.7 | |
| ML0398 | 3 | d-Ribose binding protein | 36,939.9 | |
| ML0447 | 10 | Conserved hypothetical protein | 17,104.5 | |
| ML0458 | 7 | Oxidoreductase | 32,874.6 | |
| ML0578 | 7 | Phosphoenolpyruvate carboxylase | 102,515 | |
| ML1419 | 9 | Regulatory protein | 60,968.8 | |
| ML1553 | 2 | Prolyl tRNA synthetase | 53,584.9 | |
| ML2177 | 7 | Uridine phosphorylase | 35,081.0 | |
| ML2341 | 9 | Transcriptional regulatory protein | 78,379.4 | |
| ML2346 | 10 | Conserved hypothetical protein | 33,938.9 | |
| ML2498 | 1 | Enoyl-CoA hydratase | 23,119.4 | |
| ML2649 | 7 | Oligosaccharide deacetylase | 29,553.7 | |
| III | ML0376 | 3 | Membrane protein | 36,916.8 |
| ML0410 | 6 | PE3 (PE family protein) | 10,951.4 | |
| ML0466 | 3 | Secreted protein | 32,914.4 | |
| ML0568 | 3 | Secreted protein | 18,361.6 | |
| ML0842 | 7 | Cysteine desulfurase | 44,537.5 | |
| ML1053 | 6 | PE5 (PE family) | 10,117.0 | |
| ML1055 | 3 | EsxK1 (ESAT-6 family) | 11,298.6 | |
| ML1056 | 3 | EsxL1 (ESAT-6 family) | 10,260.2 | |
| ML1182 | 6 | PPE9 (PPE family) | 43,119.6 | |
| ML1795 | 0 | HSP 18 | 16,706.9 | |
| ML1828 | 6 | PPE12 (PPE family) | 59,192.3 | |
| ML2088 | 7 | Putative cytochrome P450 | 47,154.3 | |
| ML2242 | 10 | Conserved hypothetical protein | 25,730.2 | |
| ML2531 | 3 | EsxH (ESAT-6 family) | 10,392.6 | |
| ML2532 | 3 | EsxG (ESAT-6 family) | 10,191.3 | |
| ML2534 | 6 | PE10 (PE family) | 10,243.6 | |
| ML2667 | 3 | Membrane transport protein | 65,080.5 |
a
Functional categories: 0, virulence, detoxification, adaptation; 1, lipid metabolism; 2, information pathways; 3, cell wall and cell processes; 6, PE/PPE; 7, intermediate metabolism and respiration; 8, unknown; 9, regulatory proteins; 10, conserved hypothetical.