TABLE 3.
Reciprocal antibody endpoint titers of baboon serum against candidate surface proteinsa
| Protein designation | Titer at indicated day post tick infestation
|
||||
|---|---|---|---|---|---|
| 0 | 42 | 90 | 180 | 365 | |
| BbA15 (OspA) | <100 | <100 | <100 | <100 | <100 |
| BbB19 (OspC) | <100 | 800 | 12,800 | 6,400 | 3,200 |
| Bb0147 (FlaB) | <100 | 6,400 | 3,200 | 3,200 | 3,200 |
| Bb0405 | <100 | 1,600 | 1,600 | 1,600 | 1,600 |
| Bb0689 | <100 | 6,400 | 3,200 | 1,600 | 1,600 |
| BbA36 | <100 | 12,800 | 12,800 | 3,200 | 3,200 |
| BbA64 | <100 | 6,400 | 3,200 | 1,600 | 800 |
| BbA66 | <100 | 3,200 | 3,200 | 1,600 | 400 |
| BbA69 | <100 | 200 | 400 | 200 | 200 |
| BbI42 | <100 | 200 | 200 | 400 | 200 |
A total of 100 ng of recombinant protein for each candidate surface protein was subjected to ELISA using serum from tick-infested baboons at time points 0, 42, 90, 180, and 365 days post tick infestation.