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Survival among mice lacking CD28, CD40L, IL-4, or IFN-γ. Mice were orally inoculated with 5 × 108 CFU of C. rodentium at day 21 of age. (A) Wild-type C57BL/6 mice (n = 12 mice). (B) IL-4−/− mice (n = 6 mice). (C) CD28−/− mice (n = 6 mice). (D) CD40L−/− mice (n = 9 mice). (E) IFN-γ−/− mice (n = 7 mice).
