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Transfer of acute-phase serum to CD4−/− recipients. Shown are results from CD4−/− mice receiving saline (squares; 5 mice), preimmune serum from naïve C57BL/6 mice (triangles; 5 mice), or serum from acutely infected wild-type (crosses; 5 mice), CD40L−/− (inverted triangles; 7 mice), or IFN-γ−/− mice (diamonds; 5 mice). The crosses (representing wild type) and diamonds (representing IFN-γ−/− donors) overlap.
