FIG. 8.

Burden of C. rodentium in adoptively transferred CD4^−/− mice. Shown are colonic (A) and splenic (B) CFU of C. rodentium at 15 days of infection. The y axis denotes log₁₀ CFU of C. rodentium per gram of tissue. The x axis indicates the mouse strain and cell populations transferred to CD4^−/− mice. Squares, wild-type C57BL/6 mice; triangles, CD4^−/− recipients receiving medium only; inverted triangles, CD4^−/− recipients receiving wild-type CD4 T cells; diamonds, CD4^−/− recipients receiving CD28^−/− CD4⁺ T cells; circles, CD4^−/− recipients receiving CD40L^−/− CD4⁺ T cells; asterisks, CD4^−/− recipients receiving IFN-γ^−/− CD4⁺ T cells.