TABLE 2.
Statistical analyses of C. elegans kill assaysa
| Strain | LT50b | P valuec (MG1655) | P valued (E2348/69) |
|---|---|---|---|
| MG1655 | 247 ± 16 | 0.03* | |
| E2348/69 | 161 ± 34 | 0.03* | |
| JPN15 | 150 ± 15 | 0.03* | 0.6 |
| CVD452 | 149 ± 26 | 0.006* | 0.7 |
| SE796 | 175 ± 40 | 0.06 | 0.3 |
| B171-8 | 185 ± 9 | 0.02* | 0.5 |
| B171-8ΔA | 181 ± 33 | 0.1 | 0.7 |
| TB135A | 161 ± 46 | 0.07 | 0.95 |
| TB156A | 157 ± 36 | 0.1 | 0.9 |
Nematodes were subjected to infection with EPEC and control bacteria on NGM agar at 26°C, and survival was monitored as described in Materials and Methods.
Mean LT50 values from at least three replicate assays using 12 nematodes each are presented in mean hours ± 1 SD.
Obtained by paired t test comparing LT50 values with those obtained for control strain MG1655. Asterisks indicate P values of <0.05.
Obtained by paired t test comparing LT50 values with those obtained for prototypical EPEC strain E2348/69. Asterisks indicate P values of <0.05.