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Structure of sphingolipids. Sphingolipids, such as IPC, sphingomyelin, and GlcCer contain a long-chain sphingoid base backbone (highlighted in gray) linked to a fatty acid via an amide bond with the 2-amino group and to a polar head group at the C-1 position via an ester bond. In contrast, glycerolipids, such as phosphatidylcholine, have a glycerol backbone.
