TABLE 2.
Prevention of ALA in gerbils by vaccination
| Immunization group | No. of gerbils with ALA/total no. of gerbils in expt:
|
Presence of viable parasitesa | % Efficacyb | ||
|---|---|---|---|---|---|
| 1 | 2 | 3 | |||
| CpG | 6/8 | 9/9 | 9/11 | + | ND |
| GpC + Gal-lectin | 4/6 | 4/10 | 5/11 | + | 50 |
| CpG + Gal-lectin | 0/11 | 0/11 | 0/11 | − | 100* |
a
ALA contents were aspirated and viable trophozoites determined by cultured in vitro. +, viable parasites present; −, viable parasites absent.
b
All gerbils were sacrificed at day 20 postinfection to determine vaccine efficacy. ND, not determined. An asterisk indicates a significant difference between groups (P < 0.05).