AAG	α1-acid glycoprotein
Akt	protein kinase B
AMPK	AMP-activated protein kinase
ATP	adenosine triphosphate
ATF4	activating transcription factor 4
ATF6	activating transcription factor 6
Bak	Bcl-2 homologous antagonist/killer
Bax	Bcl-2-associated X protein
Bcl-2	B-cell lymphoma 2
Bcl-xL	B-cell lymphoma-extra large
BDNF	brain-derived neurotrophic factor
BiP	binding immunoglobulin protein
Ca2+	calcium ion
CaV1.3	voltage-gated calcium channel subtype 1.3
CHOP	C/EBP homologous protein
CISD2	CDGSH iron-sulfur domain-containing protein 2
CNS	central nervous system
CYP	cytochrome P450
DRG	dorsal root ganglion
DRP1	dynamin-related protein 1
DUSP1	dual-specificity phosphatase 1
eIF2α	eukaryotic initiation factor 2 alpha
ER	endoplasmic reticulum
ER/SR	endoplasmic/sarcoplasmic reticulum
GABA	γ-aminobutyric acid
GABA-A receptor	γ-aminobutyric acid type A receptor
GPX4	glutathione peroxidase 4
GSK-3β	glycogen synthase kinase-3 beta
HaCaT	human keratinocyte cell line
HCN	hyperpolarization-activated cyclic nucleotide-gated channel
hiPSC-CM	human induced pluripotent stem cell-derived cardiomyocyte
Ih	hyperpolarization-activated current
IL-6	interleukin 6
IL-10	interleukin 10
IRE1	inositol-requiring enzyme 1
KATP	adenosine triphosphate-sensitive potassium channel
Kv3	voltage-gated potassium channel 3
LAST	local anesthetic systemic toxicity
lncRNA	long non-coding RNA
M2 receptor	muscarinic acetylcholine receptor subtype 2
MBP	myelin basic protein
METTL3	methyltransferase-like 3
mRNA	messenger RNA
mTOR	mechanistic target of rapamycin
MYC	MYC proto-oncogene
Na+/K+-ATPase	sodium–potassium adenosine triphosphatase
NaV	voltage-gated sodium channel
NaV1.5	cardiac voltage-gated sodium channel isoform 1.5
NCOA4	nuclear receptor coactivator 4
NMDA receptor	N-methyl-D-aspartate receptor
NMR	nuclear magnetic resonance
OPC	oligodendrocyte precursor cell
p53	tumor protein p53
PARP-1	poly(ADP-ribose) polymerase 1
PC12	rat pheochromocytoma cell line
PERK	protein kinase R-like endoplasmic reticulum kinase
PI3K	phosphoinositide 3-kinase
PINK1	PTEN-induced kinase 1
PK/PD	pharmacokinetic/pharmacodynamic
pKa	acid dissociation constant
PR interval	electrocardiographic interval from atrial depolarization to ventricular depolarization
PRISMA	Preferred Reporting Items for Systematic Reviews and Meta-Analyses
QRS complex	electrocardiographic marker of ventricular depolarization
QT interval	electrocardiographic interval from ventricular depolarization to repolarization
ROS	reactive oxygen species
SH-SY5Y	human neuroblastoma cell line
SK2	small-conductance calcium-activated potassium channel type 2
SLC7A11	solute carrier family 7 member 11
SR	sarcoplasmic reticulum
TASK	TWIK-related acid-sensitive potassium channel
TCA	tricarboxylic acid
TNF-α	tumor necrosis factor alpha
TRAF2	tumor necrosis factor receptor-associated factor 2
TREK-1	TWIK-related potassium channel 1
TUG1	taurine-upregulated gene 1
XBP1	X-box binding protein 1
xCT	cystine/glutamate antiporter