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Targeted cell detection by using SERS. (a) Cell-suspension scheme for SERS detection. Light from a laser diode (785 nm) was delivered through a fiber-optic probe to a suspension of KS1767 cells; the same fiber-optic probe collected and delivered the Raman signal. (b) SERS and spectra of cells incubated with Au–phage: Au–RGD-4C-imid (blue line), Au–fd-tet-imid (red line), and RGD-4C phage (green line; control, no Au) in suspension.
