TABLE 2.
Antimicrobial activities of rtCATH_1(R146-P181), rtCATH_2(R143-I178) and bovine cyclic dodecapeptide (Bovdode)
| Organism and strain | Relevant strain or phenotype | MIC/MBC (μM)
|
||
|---|---|---|---|---|
| Bovdode | rtCATH_1(1-36) | rtCATH_2(1-36) | ||
| Gram negative | ||||
| Escherichia coli NCIMB 12210 | ATCC 25922 | 5/10 | 1/20 | 2.5/5 |
| Aeromonas salmonicida MT004 | A-layer negative | 16/64 | 5/40 | 1/20 |
| A. salmonicida MT423 | A-layer positive | >64/>64 | 10/>64 | 5/16 |
| Photobacterium damselae MT1415 | Capsulated | 40/40 | 1/2.5 | 0.5/2.5 |
| P. damselae EPOY 8803 II | Noncapsulated | 2/5 | 2.5/5 | 1/8 |
| Vibrio anguillarum MT1741 | Serogroup O1 | 10/40 | 0.5/20 | 2.5/20 |
| V. anguillarum MT1742 | Serogroup O2 | 2.5/10 | 2/64 | 4/>64 |
| Yersinia ruckeri MT252 | 16/40 | 8/40 | 8/40 | |
| Gram positive | ||||
| Lactococcus garvieae MT2055 | Noncapsulated | 6/50 | 4/>64 | 8/>64 |
| L. garvieae MT2059 | Noncapsulated | 3/50 | 2/>64 | 4/>64 |
| L. garvieae MT2290 | Capsulated | 1.5/25 | 0.2/>64 | 0.2/>64 |
| L. garvieae MT2291 | Capsulated | 0.8/50 | 0.1/>64 | 0.1/>64 |