TABLE 2.

Pharmacokinetic parameters of prodrug BAL8557 estimated after single intravenous infusions of BAL8557^a

Parameter	Dose
	50 mg	100 mg	200 mg
AUClast (μg·h/ml)	0.017 (±0.005)	0.092 (±0.073)	0.279 (±0.145)
Cmax (μg/ml)	0.031 (±0.007)	0.121 (±0.107)	0.351 (±0.179)
Tmax (h)	0.50 (0.25-1.0)	0.38 (0.25-0.75)	0.75 (0.25-0.75)

^aInfusion doses were equivalent to 50, 100, and 200 mg of BAL4815. Results shown are from six subjects. Values are presented as arithmetic means plus or minus SD; median and range are listed for T_max.