Table 1.
Characteristics and outcomes of frail and non-frail patients with colorectal cancer.
| Characteristics | Total patients (N = 4,936) |
Non-Frail patients (N = 3,877) |
Frail patients (N = 1,059) |
P |
|---|---|---|---|---|
| Age | 69.00 (64.00, 74.00) | 68.00 (64.00, 74.00) | 71.00 (66.00, 77.00) | < 0.001 |
| Sex | 0.621 | |||
| Male | 2,969 (60.15) | 2,339 (60.33) | 630 (59.49) | |
| Female | 1,967 (39.85) | 1,538 (39.67) | 429 (40.51) | |
| Emergency admission | < 0.001 | |||
| YES | 686 (13.90) | 474 (12.23) | 212 (20.02) | |
| NO | 4,250 (86.10) | 3,403 (87.77) | 847 (79.98) | |
| Admission severity | < 0.001 | |||
| Critical illness | 744 (15.07) | 516 (13.31) | 228 (21.53) | |
| Stable condition | 4,192 (84.93) | 3,361 (86.69) | 831 (78.47) | |
| Adjusted Inpatient costs (CNY) |
78,582.56
(64,975.96, 99,318.49) |
77,008.71
(64,036.12, 96,974.30) |
83,967.47
(68,657.96, 107,931.20) |
< 0.001 |
| Length of stay | 13.00 (10.00, 17.00) | 13.00 (10.00, 16.00) | 15.00 (11.00, 21.00) | < 0.001 |
| Comorbidity index | 0.00 (0.00, 14.00) | 0.00 (0.00, 14.00) | 4.00 (0.00, 14.00) | < 0.001 |
| Unplanned return to the operating room | < 0.001 | |||
| Yes | 81 (1.64) | 47 (1.21) | 34 (3.21) | |
| NO | 4,855 (98.36) | 3,830 (98.79) | 1,025 (96.79) | |
| Adverse events | < 0.001 | |||
| YES | 129 (2.61) | 58 (1.50) | 71 (6.70) | |
| NO | 4,807 (97.39) | 3,819 (98.50) | 988 (93.30) | |
| Complications | < 0.001 | |||
| Yes | 46 (0.93) | 7 (0.18) | 39 (3.68) | |
| No | 4,890 (99.07) | 3,870 (99.82) | 1,020 (96.32) | |
| Tumor stage | 0.586 | |||
| Metastatic | 1,213 (24.57) | 946 (24.40) | 267 (25.21) | |
| Non-metastatic | 3,723 (75.43) | 2,931 (75.60) | 792 (74.79) | |
| Surgical approach | 0.007 | |||
| Minimally Invasive Surgery | 3,660 (74.15) | 2,909 (75.03) | 751 (70.92) | |
| Open Surgery | 1,276 (25.85) | 968 (24.97) | 308 (29.08) |
Continuous variables are presented as median (interquartile range) and were compared using the Mann–Whitney U test. Categorical variables are presented as n (%) and were compared using the chi-square test or Fisher’s exact test, as appropriate. Inpatient costs were adjusted to 2024 CNY.