TABLE 3.
Comparison of moxifloxacin susceptibilities of selected species of Bacteroides isolated from human intra-abdominal sources reported from four studies
| Studya | Total no. of isolates | Yr range | MIC50/MIC90 (GM MIC) (μg/ml) for:
|
|||||
|---|---|---|---|---|---|---|---|---|
| B. fragilis | B. thetaiotaomicron | B. ovatus | B. distasonis | B. uniformis | B. vulgatus | |||
| RMA | 360 | 2001-2004 | 0.5/8 (0.7) | 1/4 (1.5) | 2/16 (2.9) | 0.5/8 (0.6) | 2/16 (3.1) | 1/16 (2.1) |
| Edmiston | 290 | 1999-2002 | 0.5/1 (97%)c | 2/2 | 2/2 | 0.5/2 | 0.5/4 | 0.5/2 |
| Snydman | 567 | 1999-2000 | 1/8 (1.5) | 2/32 (4.2) | 4/32 (4.1) | 2/32 (2.8) | 8/32 (6.2) | 32/128 (15) |
| Horn | 55/200b | 1996-1997 | 0.25/8 | 2/4 | NAd | NA | NA | 2/64 |
RMA, current study; Edmiston, reference 7; Snydman, reference 21; Horn, reference 12.
Horn and Robson studied 200 isolates with sources as follows: surgical wounds, 57; abdominal fluids, 55; skin ulcers, 33; abscesses, 15; and other sites, 20.
Percent susceptible at 4 μg/ml.
NA, not available.