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Compound 3 inhibits QS-regulated functions in B. cenocepacia H111. Various phenotypes of B. cenocepacia H111 grown in the absence or presence of compound 3 were determined. The QS mutant H111-I was included as a control. (A) Extracellular proteolytic activity; (B) swarming motility; (C) expression of the virulence factor AidA; (D) biofilm formation; (E) killing of the nematode C. elegans.
