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. 2026 Aug 3;18(15):2511. doi: 10.3390/nu18152511
AMP adenosine monophosphate
AMPK AMP-activated protein kinase
ARE antioxidant response element
ATG autophagy-related gene/protein
ATP adenosine triphosphate
Bcl-2 B-cell lymphoma 2
Bcl-xL B-cell lymphoma extra-large
BMAL1 brain and muscle ARNT-like 1
cGAS cyclic GMP-AMP synthase
CRP C-reactive protein
CYP2D6 cytochrome P450 2D6
CYP3A4 cytochrome P450 3A4
EC European Commission
EFSA European Food Safety Authority
eIF5A eukaryotic translation initiation factor 5A
EP300 E1A binding protein p300
EU European Union
FDA US Food and Drug Administration
FOXO forkhead box O transcription factor
GLUT4 glucose transporter type 4
GRAS generally recognized as safe
GSK-3β glycogen synthase kinase 3 beta
HbA1c glycated hemoglobin A1c
HOMA-IR homeostatic model assessment of insulin resistance
IL-6 interleukin-6
IL-8 interleukin-8
LC3 microtubule-associated protein 1A/1B-light chain 3
LDL-C low-density lipoprotein cholesterol
MMP matrix metalloproteinase
mTOR mechanistic target of rapamycin
mTORC1 mechanistic target of rapamycin complex 1
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
NLRP3 NOD-like receptor thermal protein domain associated protein 3
Nrf2 nuclear factor erythroid 2-related factor 2
P-gp P-glycoprotein
PER2 period circadian regulator 2
PGC-1α peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PI3K phosphatidylinositol 3-kinase
PINK1 PTEN-induced kinase 1
PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
RCT randomized controlled trial
ROS reactive oxygen species
SASP senescence-associated secretory phenotype
SCFA short-chain fatty acid
SEDDSs self-emulsifying drug delivery systems
SIRT1 sirtuin 1
SREBP-1c sterol regulatory element-binding protein 1c
STING stimulator of interferon genes
TNF-α tumor necrosis factor alpha
TSCM T memory stem cell
UA urolithin A