TABLE 5.

Characteristics of the 22 telithromycin-resistant S. pyogenes isolates

No. of strains	Date of isolation (mo/day/yr)	MIC (μg/ml)a (n)			Resistance genotype (n)	emm type	MLSTb	L22	L4	23S rRNA (n)
		Ery	Cli	Teli
16	29/1/2001 to 15/4/2002	≥32	≥32	8 (15), 16 (1)	erm(B)	28	52	WTc	WT	T2136C (13), T2166C (3)
3	14/12/2000 to 26/5/2002	≥32	0.125 (1), 0.25 (1), ≥32 (1)	8	erm(A) (1), erm(B) (2)	89	101	WT	WT	WT
2	19/7/2001 and 18/12/2002	≥32	≥32	8	erm(B)	12	36	WT	WT	T2136C (2)
1	29/10/2001	≥32	≥32	8	erm(B)	75	49	WT	WT	WT

^aEry, erythromycin; Cli, clindamycin; Teli, telithromycin.

^bMLST, multilocus sequence type.

^cWT, wild type.