TABLE 4.

Mutations resulting in recurrent shifting PNG sites

gp120 region and virus	Amino acid and nucleotides at PNGa							Type of mutation	Macaque no.
V2	186	187	187a	188	189	190
89.6P	N	T		S	N	T
	AAT	ACT		AGT	AAT	ACT
Variant 1	N			N	N	T		Deletion, transition	K97107
	AAT			AAT	AAT	ACT
Variant 2	N	T		N	N	T		Transition	J97168, A98069,
	AAT	ACT		AAT	AAT	ACT			T98098
Variant 3	N	T	N	N	N	T		Insertion, transition	A98069
	AAT	ACT	AAT	AAT	AAT	ACT
V5	460	461	462	462a	463	464	465
89.6P	N	S	T	E	T	E	T
	AAT	AGT	ACT	GAG	ACT	GAG	ACT
Variant 1	I	S	A	E	N	E	T	Two transversions, transition	J97156
	ATT	AGT	GCT	GAG	AAT	GAG	ACT
Variant 2			P	E	N	E	T	Two transversions	J97156
			CCT	GAG	AAT	GAG	ACT
Variant 3	N	S	A	E	N	E	T	Transition, transversion	J98071
	AAT	AGT	GCT	GAG	AAT	GAG	ACT
Variant 4	N	I	A	E	N	E	T	Transition, transversion	J98071
	AAT	ATT	GCT	GAG	AAT	GAG	ACT
Variant 5	N	S	N	K	T	D	T	Transition, transversion	L98152
	AAT	AGT	AAT	AAG	ACT	GAG	ACT
Variant 6	N	S	N	K	T	D	P	Two transversions, transition	L98152
	AAT	AGT	AAT	AAG	ACT	GAG	CCT

^aUnderlined amino acids and nucleotides indicate mutations.