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. 2026 Aug 6;18(15):2566. doi: 10.3390/nu18152566
WIBL Weightlessness-induced bone loss
AMP Atractylodes macrocephala polysaccharide
HLS Hindlimb suspension
Nrf2 Nuclear factor erythroid 2-related factor 2
HO-1 Heme oxygenase-1
ROS Reactive oxygen species
Keap1 Kelch-like ECH-associated protein 1
SOD Superoxide dismutase
SD Sprague-Dawley
Micro CT Microcomputed Tomography
ITRAQ Isobaric tags for relative and absolute quantification
3D Three-dimensional
BMD Bone mineral density
BV/TV Bone volume fraction
BS/TV Bone surface density
Tb. N Trabecular number
Tb. Th Trabecular thickness
Tb. Sp Trabecular separation
Tb. Ar Trabecular bone area
DEPs Differential expressed proteins
β-CTX Cross-linked carboxyterminal telopeptide of type I collagen
TRAP 5b Tartrate-resistant acid phosphatase 5b
ICTP Cross-linked carboxyterminal telopeptide of type I collagen
P1NP Procollagen type 1 N-terminal propeptide
BALP Bone alkaline phosphatase
CAT Catalase
GSH-Px Glutathione peroxidase
ALP Alkaline phosphatase
QRT-PCR Quantificational real-time polymerase chain reaction
IHC Immunohistochemical
SMG Simulated microgravity
2D-RWVS 2D-Rotating Wall Vessel
GO Gene ontology
KEGG Kyoto encyclopedia of genes and genomes
BP Biological process
PPI Protein–protein interaction
Runx2 Runt-related transcription factor 2
OSX Osterix
NFATc1 Nuclear factor of activated T-cells c1
Ctsk Cathepsin K