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. 2026 Jul 30;20:1899073. doi: 10.3389/fnins.2026.1899073

Table 2.

Significant white matter regions for DTI-FA, FW-FA DTI-MD, and FW-MD metrics.

Voxels p-value MNI Voxels p-value MNI
X Y Z X Y Z
JHU-ICBM-DTI-81 WM Atlas DTI-FA FW-FA
Fornix (column and body of fornix) 1 0.04 2 -4 9
Cerebral peduncle R 37 0.001 20 −14 −5
Anterior corona radiata R 48 0.007 20 −17 40
Superior corona radiata R 2 0.04 20 −17 39 5 0.004 25 −18 37
Superior corona radiata L 1 0.04 −22 −20 38
Posterior limb of internal capsule R 2 0.012 20 −14 −2
Posterior limb of internal capsule L 20 0.001 −20 −15 −4
JHU-ICBM-DTI-81 WM atlas DTI-MD FW-MD
Anterior corona radiata L 1 0.024 −24 27 23
Superior corona radiata R 11 0.006 19 −1 41 3 0.001 19 −4 42
Superior corona radiata L 11 0.001 −26 −16 31 11 0.001 −26 −12 35
Posterior corona radiata R 2 0.029 25 −24 25
Posterior limb of internal capsule L 1 0.013 −23 −10 15
Cingulum (cingulate gyrus) L 2 0.023 −8 −2 33
Body of corpus callosum 1 0.017 −11 −5 35

All reported clusters survived correction for multiple comparisons at the voxel level (p < 0.05), with cluster sizes ≥1 voxel.

FA = fractional anisotropy; MD = mean diffusivity; DTI = diffusion tensor imaging; FW-DTI = free-water-corrected diffusion tensor imaging; FW-FA = free-water-corrected fractional anisotropy; FW-MD = free-water-corrected mean diffusivity; R = right; L = left. JHU-ICBM-DTI-81 WM atlas = Johns Hopkins University International Consortium for Brain Mapping DTI-81 white matter atlas.