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. 2026 Jul 27;31(15):2612. doi: 10.3390/molecules31152612
ADMET Absorption, Distribution, Metabolism, Excretion, and Toxicity
AKT Protein Kinase B (PKB)
BBB Blood–Brain Barrier
DHEAS Dehydroepiandrosterone Sulfate
E1 Estrone
E2 Estradiol
E1S Estrone Sulfate
ER Estrogen Receptor
ER+ Estrogen Receptor-positive
ERα Estrogen Receptor alpha
ESR1 Estrogen Receptor 1 (gene)
FGly Formylglycine
GHS Globally Harmonized System
HER2 Human Epidermal Growth Factor Receptor 2
IGF1R Insulin-like Growth Factor 1 Receptor
MAPK Mitogen-Activated Protein Kinase
MD Molecular Dynamics
MM/PBSA Molecular Mechanics Poisson–Boltzmann Surface Area
NAG N-acetylglucosamine
PDB Protein Data Bank
PI3K Phosphoinositide 3-kinase
Rg Radius of Gyration
RMSD Root-Mean-Square Deviation
RMSF Root-Mean-Square Fluctuation
SBR Structure–Binding Relationship(s)
SMILES Simplified Molecular-Input Line-Entry System
STS Steroid Sulfatase
TPSA Topological Polar Surface Area