FIG. 1.

Transposition mutants of the triplex proteins. The figure shows the amino acid sequences of the VP23 (A) and VP19C (B) proteins. The arrows show the sites of the transposition insertions. The filled arrow indicates that the insertion abolished the interaction between VP19C and VP23 in the yeast two-hybrid assay, whereas, the nonfilled arrow indicates that the two proteins were still capable of interaction. Amino acids that are conserved in the alphaherpesviruses are underlined, and those in bold indicate amino acids or side chain groups that are conserved in all three herpesvirus families. Amino acids of VP23 (N102, P105, P119, P140, and P144) and VP19C (G248, G268, D296, and G409) are absolutely conserved in all three families.