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. 2026 Jul 25;26(15):4728. doi: 10.3390/s26154728

Algorithm 2 Automated Bounding Box Generation for Lesion Detection

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procedure Generate(I)
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$I_{g r a y} \leftarrow rgb 2 gray (I)$
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$T \leftarrow otsu (I_{g r a y})$
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$I_{b i n a r y} \leftarrow I_{g r a y} > T$
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$K \leftarrow ellipse (15, 15)$
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$I_{c l o s e d} \leftarrow morphClose (I_{b i n a r y}, K)$
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$I_{p r o c e s s e d} \leftarrow morphOpen (I_{c l o s e d}, K)$
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$C \leftarrow findContours (I_{p r o c e s s e d})$
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if $C = \emptyset$ then
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return $(0.5, 0.5, 0.7, 0.7)$
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else
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$c_{m a x} \leftarrow arg {max}_{c \in C} area (c)$
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$(x, y, w, h) \leftarrow boundingRect (c_{m a x})$
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$x_{c e n t e r} \leftarrow (x + w / 2) / W$
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$y_{c e n t e r} \leftarrow (y + h / 2) / H$
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$b b o x_{w} \leftarrow min (1.15 \cdot w / W, 1.0)$
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$b b o x_{h} \leftarrow min (1.15 \cdot h / H, 1.0)$
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return $(x_{c e n t e r}, y_{c e n t e r}, b b o x_{w}, b b o x_{h})$
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end if
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end procedure