Table 13.
Adjusted associations between nutrient intake and LSS radiological severity.
| Radiological outcome | Nutrient | β (per SD) | 95% CI | p | q (FDR) | n |
|---|---|---|---|---|---|---|
| Schizas grade | EPA + DHA | 0.04 | [−0.05, 0.13] | 0.407 | 0.771 | 180 |
| Schizas grade | Fiber | −0.02 | [−0.11, 0.08] | 0.749 | 0.930 | 180 |
| Schizas grade | Folate | −0.05 | [−0.13, 0.03] | 0.201 | 0.771 | 180 |
| Schizas grade | Mg | 0.03 | [−0.05, 0.11] | 0.440 | 0.771 | 180 |
| Schizas grade | Vitamin D | 0.01 | [−0.07, 0.09] | 0.874 | 0.930 | 180 |
| Schizas grade | Ca | −0.00 | [−0.08, 0.08] | 0.930 | 0.930 | 180 |
| Schizas grade | Zn | 0.03 | [−0.05, 0.12] | 0.440 | 0.771 | 180 |
| LF thickness (mm) | EPA + DHA | −0.07 | [−0.17, 0.03] | 0.154 | 0.269 | 180 |
| LF thickness (mm) | Fiber | −0.07 | [−0.18, 0.04] | 0.207 | 0.290 | 180 |
| LF thickness (mm) | Folate | 0.01 | [−0.09, 0.10] | 0.894 | 0.894 | 180 |
| LF thickness (mm) | Mg | 0.09 | [0.00, 0.19] | 0.048 | 0.168 | 180 |
| LF thickness (mm) | Vitamin D | −0.05 | [−0.14, 0.04] | 0.264 | 0.308 | 180 |
| LF thickness (mm) | Ca | 0.07 | [−0.02, 0.16] | 0.120 | 0.269 | 180 |
| LF thickness (mm) | Zn | −0.10 | [−0.19, −0.00] | 0.044 | 0.168 | 180 |
| AP canal diameter (mm) | EPA + DHA | 0.06 | [−0.15, 0.27] | 0.578 | 0.949 | 180 |
| AP canal diameter (mm) | Fiber | 0.02 | [−0.21, 0.24] | 0.885 | 0.949 | 180 |
| AP canal diameter (mm) | Folate | 0.11 | [−0.08, 0.30] | 0.252 | 0.882 | 180 |
| AP canal diameter (mm) | Mg | −0.13 | [−0.32, 0.06] | 0.189 | 0.882 | 180 |
| AP canal diameter (mm) | Vitamin D | 0.02 | [−0.17, 0.21] | 0.851 | 0.949 | 180 |
| AP canal diameter (mm) | Ca | −0.01 | [−0.20, 0.18] | 0.949 | 0.949 | 180 |
| AP canal diameter (mm) | Zn | 0.08 | [−0.11, 0.28] | 0.406 | 0.948 | 180 |
| Dural sac area (mm2) | EPA + DHA | 0.34 | [−1.86, 2.55] | 0.758 | 0.811 | 180 |
| Dural sac area (mm2) | Fiber | 0.29 | [−2.10, 2.68] | 0.811 | 0.811 | 180 |
| Dural sac area (mm2) | Folate | 2.61 | [0.65, 4.57] | 0.009 | 0.065 | 180 |
| Dural sac area (mm2) | Mg | −1.31 | [−3.33, 0.71] | 0.204 | 0.588 | 180 |
| Dural sac area (mm2) | Vitamin D | −0.33 | [−2.33, 1.67] | 0.742 | 0.811 | 180 |
| Dural sac area (mm2) | Ca | −0.48 | [−2.49, 1.53] | 0.638 | 0.811 | 180 |
| Dural sac area (mm2) | Zn | 1.20 | [−0.86, 3.26] | 0.252 | 0.588 | 180 |
| Central stenosis grade | EPA + DHA | 0.04 | [−0.05, 0.13] | 0.407 | 0.771 | 180 |
| Central stenosis grade | Fiber | −0.02 | [−0.11, 0.08] | 0.749 | 0.930 | 180 |
| Central stenosis grade | Folate | −0.05 | [−0.13, 0.03] | 0.201 | 0.771 | 180 |
| Central stenosis grade | Mg | 0.03 | [−0.05, 0.11] | 0.440 | 0.771 | 180 |
| Central stenosis grade | Vitamin D | 0.01 | [−0.07, 0.09] | 0.874 | 0.930 | 180 |
| Central stenosis grade | Ca | −0.00 | [−0.08, 0.08] | 0.930 | 0.930 | 180 |
| Central stenosis grade | Zn | 0.03 | [−0.05, 0.12] | 0.440 | 0.771 | 180 |
| Facet arthrosis grade | EPA + DHA | 0.03 | [−0.07, 0.14] | 0.544 | 0.760 | 180 |
| Facet arthrosis grade | Fiber | −0.08 | [−0.19, 0.03] | 0.154 | 0.506 | 180 |
| Facet arthrosis grade | Folate | −0.06 | [−0.15, 0.04] | 0.217 | 0.506 | 180 |
| Facet arthrosis grade | Mg | 0.08 | [−0.02, 0.17] | 0.105 | 0.506 | 180 |
| Facet arthrosis grade | Vitamin D | −0.01 | [−0.11, 0.08] | 0.760 | 0.760 | 180 |
| Facet arthrosis grade | Ca | −0.02 | [−0.12, 0.08] | 0.677 | 0.760 | 180 |
| Facet arthrosis grade | Zn | −0.04 | [−0.14, 0.05] | 0.367 | 0.643 | 180 |
| Foraminal stenosis grade | EPA + DHA | −0.05 | [−0.15, 0.05] | 0.344 | 0.647 | 180 |
| Foraminal stenosis grade | Fiber | −0.06 | [−0.17, 0.04] | 0.244 | 0.647 | 180 |
| Foraminal stenosis grade | Folate | −0.03 | [−0.12, 0.06] | 0.485 | 0.679 | 180 |
| Foraminal stenosis grade | Mg | 0.04 | [−0.05, 0.13] | 0.370 | 0.647 | 180 |
| Foraminal stenosis grade | Vitamin D | 0.00 | [−0.09, 0.09] | 0.992 | 0.992 | 180 |
| Foraminal stenosis grade | Ca | 0.01 | [−0.08, 0.10] | 0.775 | 0.905 | 180 |
| Foraminal stenosis grade | Zn | −0.09 | [−0.18, 0.00] | 0.055 | 0.388 | 180 |
| Lateral recess stenosis grade | EPA + DHA | 0.03 | [−0.09, 0.14] | 0.635 | 0.801 | 180 |
| Lateral recess stenosis grade | Fiber | 0.06 | [−0.06, 0.18] | 0.359 | 0.801 | 180 |
| Lateral recess stenosis grade | Folate | −0.09 | [−0.19, 0.01] | 0.076 | 0.532 | 180 |
| Lateral recess stenosis grade | Mg | 0.02 | [−0.08, 0.12] | 0.687 | 0.801 | 180 |
| Lateral recess stenosis grade | Vitamin D | 0.01 | [−0.10, 0.11] | 0.904 | 0.904 | 180 |
| Lateral recess stenosis grade | Ca | 0.03 | [−0.07, 0.13] | 0.533 | 0.801 | 180 |
| Lateral recess stenosis grade | Zn | 0.02 | [−0.08, 0.13] | 0.642 | 0.801 | 180 |
Multivariable models (per SD, continuous) adjusted as in Table 12, LSS cohort (n = 180). Schizas grade coded A = 1 to D = 4. No association remained significant after FDR correction. LSS, lumbar spinal stenosis; SD, standard deviation; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; Mg, magnesium; Ca, calcium; Zn, zinc; LF, ligamentum flavum; AP, anteroposterior.