Table 1.

Cox Regression Analyses of Prognostic Factors for Disease-Free Survival.

Factors	Univariate analysis		Multivariate analysis
	χ2 value	P value	HR value(95% CI)	Wald	P value
Gender	2.206	0.137
Age	2.755	0.097
Smoking History	0.427	0.808
Diabetes History	0.697	0.706
Biliary drainage	0.095	0.757
NEUT (×10⁹/L)	2.646	0.104
LYM (×10⁹/L)	2.868	0.090
MONO (×10⁹/L)	0.347	0.556
PLT (×10⁹/L)	1.967	0.161
ALB (g/L)	0.005	0.944
CA19-9 (U/mL)	0.001	0.970
GGT(U/L)	2.551	0.110
TB(mg/dL)	1.493	0.222
LMR	1.367	0.242
NLR	3.415	0.065
PLR	11.038	0.004	1.013 (0.797–5.468)	3.627	0.163
SII	3.908	0.048	1.002 (0.918–3.540)	0.018	0.894
PNI	11.031	0.001	0.953 (0.245–1.702)	5.993	0.014
Hemorrhage(ml)	0.112	0.737
Intraoperative blood transfusion	0.023	0.880
Operative time(h)	0.052	0.819
Tumor diameter(cm)	0.006	0.937
Tumor differentiation	4.562	0.033	0.996 (0.990–1.002)	1.955	0.162
Lymph node metastasis	0.573	0.449
R0/R1 resection	1.270	0.260
TNM stage	2.011	0.570
Postoperative chemotherapy	0.212	0.645
Postoperative complications	0.784	0.376
KRT6A expression	12.400	0.000	6.337 (1.733–9.540)	4.479	0.034