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NDV-F is a potent inducer of IFN-α/β in vivo. An IFN-α/β bioassay was performed on BAL supernatants to determine the level of induction 9, 24, and 48 h post-intranasal inoculation with NDV-F or RSV. Installation of allantoic fluid was used as a negative control. The asterisk indicates a statistically significant (P < 0.05) difference between the NDV-F- and RSV-treated animals.
