FIG. 6.

Effect of ionizing radiation and mitomycin C on wild-type, mRad54^−/−, mRad54B^−/−, and mRad54^−/− mRad54B^−/− ES cells. (A) Clonogenic survival of wild-type (wt) and mutant ES cells after irradiation with increasing doses of gamma rays. The percentage of surviving cells, measured by their colony-forming ability, is plotted as function of the gamma-ray dose. (B) Clonogenic survival of wild-type, mRad54^−/−, mRad54B^−/−, and mRad54^−/− mRad54B^−/− ES cells after treatment with mitomycin C. Error bars (some obscured by the symbols) represent standard errors of the means.