Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Disruption of the mce1R gene in M. tuberculosis. (A) Genomic organizations of the WT and mutant strains. Black arrowheads indicate the region cloned into the knockout vector. The region between the EagI and SacII sites was deleted and replaced by a hygromycin resistance cassette to create the mutant strain. The black bar corresponds to the probe used for hybridization. (B) Southern blot analysis of genomic DNA from WT and mutant strains digested with BclI.
