TABLE 2.
Thirty-seven protein-encoding sequences found in the genome of M. thermautotrophicus and all other methanogens except M. stadtmanae
| CDS or locus | Function according to Smith et al. (function according to our annotations)a |
|---|---|
| NP_276663 | Molybdenum cofactor biosynthesis protein MoaA |
| NP_276967 | Molybdenum cofactor biosynthesis protein MoaB |
| NP_275948 | Molybdenum cofactor biosynthesis protein MoaC |
| NP_276138 | Molybdenum cofactor biosynthesis protein MoeA |
| NP_276820 | Carbon monoxide dehydrogenase, alpha subunit (CO dehydrogenase/acetyl-CoA synthase, subunit alpha) |
| NP_276822 | Carbon monoxide dehydrogenase, alpha subunit (CO dehydrogenase/acetyl-CoA synthase, subunit beta) |
| NP_276825 | Corrinoid/iron-sulfur protein, large subunit (CO dehydrogenase/acetyl-CoA synthase, subunit gamma) |
| NP_276824 | Corrinoid/iron-sulfur protein, small subunit (CO dehydrogenase/acetyl-CoA synthase, subunit delta) |
| NP_276823 | Nitrogenase reductase-related protein (CO dehydrogenase/acetyl-CoA synthase, accessory protein) |
| NP_276732 | Thiamine biosynthetic enzyme |
| NP_276299 | Phosphonoacetaldehyde methylase |
| NP_277018 | Possible protein methyltransferase (predicted RNA methylase) |
| NP_276283 | Na+/Ca+ exchanging protein related |
| NP_276665 | Formate dehydrogenase, alpha subunit homologue |
| NP_276615 | Phenylalanyl-tRNA synthetase alpha subunit |
| NP_276113 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (predicted NAD-dependent aldehyde dehydrogenase) |
| NP_275964 | l-Isoaspartyl protein carboxyl methyltransferaseb |
| NP_277015 | Hypothetical protein (putative RNA 3′-terminal phosphate cyclase) |
| NP_275838 | Hypothetical protein (predicted ABC-type transport system, permease protein) |
| NP_276300 | Possible cation transporter |
| NP_276301 | Cell division inhibitor-related protein |
| NP_276195 | Acetyltransferase |
| NP_276886 | Stomatin-like protein |
| NP_275744 | Conserved protein (contains ferredoxin domain) |
| NP_276442 | Hypothetical proteinb |
All CDS of M. thermautotrophicus (86) were searched with the BLAST program against the genomes of all other methanogenic archaea sequenced so far. CDS of M. thermautotrophicus with BLAST hits better than e−15 in all other genomes except that of M. stadtmanae are listed. Only the first CDS is listed when there was more than one hit resulting from different CDS with high levels of sequence similarity in the M. thermautotrophicus genome.