TABLE 5.

eIF2 is not specifically required for SLBP translation function

Condition and cell type	No SLBP (light units, 106)			SLBP (light units, 106)
	SLR	SLWT	SLWT/SLR	SLR	SLWT	SLWT/SLR
Nonstarved
eIF2α/GCN2	0.17 ± 0.04	0.20 ± 0.04	1.2	0.13 ± 0.03	1.67 ± 0.58	13
eIF2α/gcn2	0.29 ± 0.05	0.31 ± 0.07	1.1	0.10 ± 0.06	1.79 ± 0.72	18
eIF2α-S51A/GCN2	0.12 ± 0.03	0.15 ± 0.04	1.3	0.07 ± 0.04	1.53 ± 0.56	22
eIF2α-S51D/GCN2	0.19 ± 0.03	0.25 ± 0.02	1.3	0.07 ± 0.02	1.19 ± 0.61	17
Starved
eIF2α/GCN2	0.48 ± 0.09	0.68 ± 0.07	1.4	0.80 ± 0.17	0.90 ± 0.60	1.1
eIF2α/gcn2	0.26 ± 0.05	0.22 ± 0.02	0.8	0.72 ± 0.17	2.54 ± 0.60	3.5
eIF2α-S51A/GCN2	1.45 ± 0.30	1.48 ± 0.10	1.0	0.97 ± 0.12	1.14 ± 0.28	1.2
eIF2α-S51D/GCN2	1.37 ± 0.25	0.88 ± 0.38	0.6	2.34 ± 0.15	3.02 ± 0.99	1.3