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. Author manuscript; available in PMC: 2026 Aug 15.
Published in final edited form as: Comput Methods Programs Biomed. 2026 Jun 8;285:109474. doi: 10.1016/j.cmpb.2026.109474

Table 2.

Comparative performance analysis of AFIB detection methods on the PTB-XL-Improved test set and the original PTB-XL test set. All methods were trained and evaluated as 12-lead ECG classifiers using the same patient-level train–test split. For the encoder–decoder, repeated training across 13 random seeds yielded empirical 95% confidence intervals within ±0.1% for the reported metrics.

Method Dataset Set AUC Sensitivity Specificity F1-Score PPV
Encoder–decoder (ours) PTB-XL-Improved Test 99.15* 97.81 95.63* 96.75* 95.72*
CNN-BiLSTM [40,41] PTB-XL-Improved Test 97.15 95.62 90.62 93.29 91.06
ResNet [42,51] PTB-XL-Improved Test 97.27 98.75* 87.50 93.49 88.76
CNN [31,35–37] PTB-XL-Improved Test 79.18 82.19 60.31 74.08 67.44

Encoder–decoder (ours) Original PTB-XL Test 99.78* 99.01* 98.02 98.52* 98.04*
CNN-BiLSTM [40,41] Original PTB-XL Test 98.84 97.69 92.85 95.38 93.17
ResNet [42,51] Original PTB-XL Test 99.69 97.03 98.84* 95.15 93.33
CNN [31,35–37] Original PTB-XL Test 94.29 86.14 90.10 87.88 89.69