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. 2026 Aug 14;63:e26028. doi: 10.1590/S0004-2803.24612026-028

TABLE 1. Level of evidence and study design.

Level of evidence Study design
I Systematic reviews or meta-analyses of randomized clinical trials.
II Well-designed randomized controlled clinical trial.
III Well-designed, non-randomized controlled clinical trial.
IV Cohort study, case-control study, well-designed cross-sectional study.
V Systematic review of qualitative and descriptive studies.
VI Unique descriptive or qualitative study.
VII Expert opinion and/or expert report.

Source: Author‘s own work (2024).