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. 2006 Jan 17;103(4):897–902. doi: 10.1073/pnas.0506540103

Fig. 1.

Fig. 1.

Diagrammatic representation of a single repeat of the rDNA array of S. cerevisiae and a model of a terminated replication fork. (A) The repeated sequence present in the rDNA showing the 35S region transcribed by RNA polymerase I, the 5S region transcribed by RNA polymerase III, nontranscribed spacer I (NTS1) that contains tandem Ter sites and the nontranscribed spacer II (NTS2) that contains an origin of bidirectional replication (ARS). (B) A model of a terminated fork showing the locations of the two Ter sites that are bound to Fob1p, the putative replicative helicase MCM2–7p, the proliferating cell nuclear antigen sliding clamp (lavender ring), the Tof1p–Csm3p protein complex that either directly or indirectly antagonizes the Rrm3p helicase that progresses 5′ to 3′ on DNA and tends to release the terminated forks probably by transiently displacing Fob1p.