Fig. 2.

Effect of platelet depletion on angiogenesis in Matrigel assay. Matrigels containing 80 ng of bFGF were implanted s.c. and recovered on day 7 after implantation. (A) Representative photographs of gross morphology of Matrigel implants from mice injected with IgG (Upper) and mice injected with antiplatelet antibody (Lower). (B) Hematoxylin and eosin staining of Matrigel sections from the mice injected with IgG (Left) and from the platelet-depleted mice (Right). Note the numerous extravascular RBCs in Right.