3O-C12-HSL stimulation of T cells induces Th1-type cytokines but not Th2. Purified T cells were activated with ova peptide and APCs and stimulated with IL-12 (100 U), IL-4 (1,000 U), or 3O-C12-HSL (5 μM). Data are expressed as the percentage of cytokine produced in comparison to the control (cultures containing only T cells, ova peptide, and APCs). Error bars indicate standard deviations.