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Cox-2 expression is induced in skin after 3O-C12-HSL stimulation. Mice were given dermal injections of PBS or 10 μM 3O-C12-HSL, and after 24 h skin sections were stained with an anti-Cox-2 antibody. As a control for background staining, a blocking peptide (BP) was added to the antibody prior to incubation with samples. The red precipitate in the sections shows the expression of Cox-2 in the samples. Samples were counterstained with hematoxylin. Arrows indicate areas of staining.
