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. 2026 Aug 4;14:1797663. doi: 10.3389/fpubh.2026.1797663

Table 2.

Unadjusted (bivariate) linear regression analyses of factors associated with financial toxicity (FACIT-COST) and psychological distress (PHQ-4).

Predictor Category (vs. reference) FACIT-COST β p-value PHQ-4 β p-value
Age (years) Per 1-year increase 0.05 0.64 −0.01 0.87
Gleason risk group Intermediate vs. High 5.59 0.002 −1.92 0.004
Low vs. High 8.54 0.029 −1.86 0.202
Insurance type Private vs. No coverage 7.36 0.008 −1.20 0.254
Public vs. No coverage 0.39 0.88 0.59 0.54
Treatment modality Local vs. Combined 5.29 0.008 −1.55 0.039
Systemic only vs. Combined −2.72 0.22 0.28 0.74
Actual treatment coverage None vs. Full −12.00 < 0.001 2.11 0.016
Partial vs. Full −8.85 < 0.001 2.04 0.011
Treatment disruption Interruption vs. Delay 2.87 0.33 −1.11 0.33
None vs. Delay 13.40 < 0.001 −4.53 < 0.001
Monthly household income Low vs. High −17.70 < 0.001 5.51 < 0.001
Medium vs. High −7.57 < 0.001 2.22 0.002
Comorbidities Yes vs. No −0.81 0.68 0.56 0.43

(FACIT-COST and PHQ-4 scores analyzed as continuous outcomes. β coefficients represent unadjusted associations relative to reference categories.) FACIT-COST, functional assessment of chronic illness therapy–cost; PHQ-4, patient health questionnaire-4.