Table 2.
Unadjusted (bivariate) linear regression analyses of factors associated with financial toxicity (FACIT-COST) and psychological distress (PHQ-4).
| Predictor | Category (vs. reference) | FACIT-COST β | p-value | PHQ-4 β | p-value |
|---|---|---|---|---|---|
| Age (years) | Per 1-year increase | 0.05 | 0.64 | −0.01 | 0.87 |
| Gleason risk group | Intermediate vs. High | 5.59 | 0.002 | −1.92 | 0.004 |
| Low vs. High | 8.54 | 0.029 | −1.86 | 0.202 | |
| Insurance type | Private vs. No coverage | 7.36 | 0.008 | −1.20 | 0.254 |
| Public vs. No coverage | 0.39 | 0.88 | 0.59 | 0.54 | |
| Treatment modality | Local vs. Combined | 5.29 | 0.008 | −1.55 | 0.039 |
| Systemic only vs. Combined | −2.72 | 0.22 | 0.28 | 0.74 | |
| Actual treatment coverage | None vs. Full | −12.00 | < 0.001 | 2.11 | 0.016 |
| Partial vs. Full | −8.85 | < 0.001 | 2.04 | 0.011 | |
| Treatment disruption | Interruption vs. Delay | 2.87 | 0.33 | −1.11 | 0.33 |
| None vs. Delay | 13.40 | < 0.001 | −4.53 | < 0.001 | |
| Monthly household income | Low vs. High | −17.70 | < 0.001 | 5.51 | < 0.001 |
| Medium vs. High | −7.57 | < 0.001 | 2.22 | 0.002 | |
| Comorbidities | Yes vs. No | −0.81 | 0.68 | 0.56 | 0.43 |
(FACIT-COST and PHQ-4 scores analyzed as continuous outcomes. β coefficients represent unadjusted associations relative to reference categories.) FACIT-COST, functional assessment of chronic illness therapy–cost; PHQ-4, patient health questionnaire-4.