FIG. 3.

Activation or repression of selected genes in S. aureus removed from subcutaneous infection chambers at the indicated times compared to gene expression by S. aureus in the inoculum. Expression values are plotted for S. aureus removed from the nonimmmune rabbits 2 h after inoculation and from the SEB-immune rabbits 2 and 8 h after inoculation. Data are plotted against a logarithmic scale. Values are averages of data from experiments conducted with four rabbits (two immune and two nonimmune), each of which was evaluated using triplicate DNA microarrays. Standard errors of the means are indicated. Those genes whose expression was significantly affected (P < 0.05 by Student's t test) at 2 h after inoculation by immunization against SEB are indicated by an asterisk.