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. 2026 Aug 5;17:1818773. doi: 10.3389/fendo.2026.1818773

Table 2.

Associations of objective sleep characteristics with the risk of incident osteoporosis.

Characteristic HR 95% CI P
Model 1
 Average sleep duration 0.93 0.89-0.98 0.005
 Sleep efficiency 0.92 0.88-0.97 <0.001
 Sleep regularity index 0.97 0.93-1.02 0.302
 Sleep midpoint 1.02 0.97-1.07 0.360
 Relative amplitude 0.85 0.81-0.88 <0.001
Model 2
 Average sleep duration 0.90 0.86-0.95 <0.001
 Sleep efficiency 0.91 0.87-0.96 <0.001
 Sleep regularity index 0.93 0.88-0.98 0.004
 Sleep midpoint 1.05 1.00-1.11 0.036
 Relative amplitude 0.77 0.74-0.81 <0.001
Model 3
 Average sleep duration 0.91 0.87-0.95 <0.001
 Sleep efficiency 0.92 0.88-0.97 0.001
 Sleep regularity index 0.98 0.93-1.03 0.362
 Sleep midpoint 1.03 0.98-1.08 0.281
 Relative amplitude 0.80 0.76-0.85 <0.001

HR, Hazard Ratio; CI, Confidence Interval.