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. 2026 Aug 5;17:1860011. doi: 10.3389/fimmu.2026.1860011

Figure 1.

Flowchart summarizing the identification, exclusion, and inclusion of study participants: starting with 907 deceased infants identified, 218 meeting ICD-10 code criteria, 63 excluded per specific medical conditions, 155 reviewed clinically, 54 excluded after review, 96 samples verified, 79 parental consents obtained, resulting in a final study population for genetic testing of 52 SIDS and 27 infection cases.

Study inclusion workflow. CoDR, Norwegian cause of death registry; DIC, disseminated intravascular coagulation; SIDS, sudden infant death syndrome; IEI, inborn error of immunity; †A detailed overview of all the ICD-10 codes for inclusion is provided in Supplementary Table 1. *Two patients with DIC were excluded; one patient was affected by Rhesus isoimmunization (ICD-10=P55.0), the other was affected by placental transfusion syndrome (ICD-10=P02.3), both of which were considered as more likely causes of DIC rather than an undiagnosed infection. **One patient with Down's syndrome (ICD-10=Q90.9) and infection with Epstein-Barr virus (ICD-10=B27.0) was included as death caused by this virus is unusual.