Table 1.
Demographic, immunological and genetic characteristics of 79 deceased infants ≤2 years old in Norway from 2012 to 2017.
| Variables | Total n = 79 (100%) | SIDS n = 52 (66%) | Infection n = 27 (34%) |
|---|---|---|---|
| Median age, days (IqR) | 80 (229) | 117 (237) | 51 (412) |
| Age at death <120 days | 45 (57) | 27 (52) | 18 (67) |
| Prematurity, gestational age <37 weeks | 19 (24) | 10 (19) | 9 (33) |
| Males | 53 (67) | 35 (67) | 18 (67) |
| Median TREC, µl (IqR) | 250 (150) | 267 (186) | 208 (139) |
| All infants with at least one gene variant | 55 (70) | 35 (67) | 20 (74) |
| MBL2 variants | 33 (42) | 19 (37) | 14 (52) |
| VUS in autosomal dominant disease genes* | 14 (18) | 13 (25) | 1 (4) |
| One pathogenic variant in autosomal recessive disease genes** | 18 (23) | 8 (15) | 10 (37) |
SIDS, sudden infant death syndrome; IqR, interquartile range; TREC, T-cell exicion circles; MBL, mannose-binding lectin; VUS, variants of uncertain significance; *None of the variants were clearly pathologic; **Including individuals with variants in >1 genes; parentheses are percentages of the total in each group unless specified otherwise.