Table 2.

Exploratory regression analyses exploiting possible predictive factors for the administration of both IL-1 or IL-6 inhibitors in assessed patients with AOSD.

Clinical variables	OR	95% CI	P-value
Administration of IL-1 inhibitor
Univariate analyses
Age years	0.99	0.97-1.02	0.314
Male sex	1.09	0.58-2.05	0.789
CRP mg/L	0.99	0.98-1.01	0.078
CRP ≥68.7 mg/L	1.34	0.45-1.62	0.631
Ferritin ng/ml	1.01	0.96-1.04	0.088
Ferritin ≥1225.0 ng/ml	3.01	1.87-7.20	0.004
Multivariate analysis with CRP and Ferritin used as continuous variables
Age years	0.99	0.97-1.09	0.056
Male sex	1.06	0.28-2.45	0.872
CRP mg/L	0.99	0.97-1.01	0.434
Ferritin ng/ml	1.01	0.98-1.02	0.073
Multivariate analysis with CRP≥68.7 mg/L and Ferritin≥1225.0 ng/ml
Age years	0.99	0.97-1.01	0.533
Male sex	1.06	0.55-2.04	0.857
CRP ≥68.7 mg/L	1.18	0.58-2.40	0.657
Ferritin ≥1225.0 ng/ml	2.81	1.36-5.81	0.005
Administration of IL-6 inhibitor
Univariate analyses
Age years	1.03	1.01-1.07	0.046
Male sex	1.09	0.58-2.05	0.789
CRP mg/L	0.98	0.96-1.01	0.068
CRP ≥68.7 mg/L	0.99	0.98-1.02	0.065
Ferritin ng/ml	0.87	0.44-3.09	0.985
Ferritin ≥1225.0 ng/ml	0.99	0.97-1.01	0.098

OR, odds ratio; CI, confidence interval; CRP, C reactive protein.

Statistically significant values are shown in bold.