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. 2026 Aug 5;17:1852661. doi: 10.3389/fimmu.2026.1852661

Table 3.

Comparison between the findings of the present study and the latest EULAR/PReS recommendations.

The EULAR/PReS recommendations about treatment* Main items of the recommendations Our findings Compliance between recommendation items and our findings
To avoid prolonged systemic GC use for achieving and maintaining the target, the use of IL-1 and IL-6 inhibitors should be prioritised due to high evidence of efficacy. GC use can be markedly limited, or even avoided. 97.7% treated with GCs. No concordance in our real-world data.
Evidences supporting the use of cs DMARDs is scarce. 58.8% treated with csDMARDs. Partial concordance in our real-world data.
An IL-1 or an IL-6 inhibitor should be initiated as early as possible when the diagnosis is established. IL-1 and IL-6 inhibitor should be initiated before 3 months from symptoms onset. 6 months to initiate a bDMARD; 22.7% started a bDMARD within the first 3 months. No concordance in our real-world data.

*Fautrel B, et al. Ann Rheum Dis. 2024;83:1614-1627.