Figure 4.

The complexity of epithelial ovarian cancer subtypes. Each subtype shows the percentage of epithelial ovarian cancer cases and the mutation frequency in those cases (purple). Then, in blue indicates the pathways or complexes affected by the frequent mutation. Moreover, in green are the cellular responses caused by the alterations in pathways. HGSC, high-grade serous ovarian cancer. LGSC, low-grade serous ovarian cancer, CCOC, clear cell ovarian carcinomas, and DDOC, dedifferentiated ovarian carcinomas. C.C., cell cycle. DNA-R, DNA-repair.