Lower urinary tract symptoms (LUTS) in men are multifactorial; both benign prostatic hyperplasia (BPH) and overactive bladder (OAB) can cause lower urinary tract symptoms (LUTS) in men.

Coexisting OAB and BPH is common; however, OAB is inadequately addressed in men, and men with both BPH and OAB tend to only receive OAB treatment after BPH management does not adequately address their LUTS.

Given the diverse nature of LUTS, a single therapeutic may not adequately address the various symptoms associated with BPH and OAB, warranting the combined management of BPH and OAB with multiple medications (i.e., OAB treatments with α-blockers).

In primary care settings, proactive discussions about symptoms may better align patients with more timely and effective treatment appropriate for their symptoms and conditions.

There is a pressing need for enhanced awareness of OAB in men and the effectiveness of OAB medications (e.g., anticholinergic medication may be an appropriate treatment for OAB and β3-adrenergic receptor agonists such as vibegron are effective with a strong safety profile) in addressing the urinary symptoms OAB presents in men.