Table 4. Univariable and multivariable generalised estimating equations analyses of factors associated with appropriate dosage of antibiotics.
| Variable | OR (95% CI) | P value (OR) | aOR (95% CI) | P value (aOR) |
|---|---|---|---|---|
| Age | ||||
| 28 days to 12 months | Ref | Ref | ||
| 0–27 days | 0.87 (0.10 to 7.88) | 0.900 | 1.02 (0.12 to 8.91) | 0.985 |
| 13–23 months | 1.37 (0.97 to 1.94) | 0.072 | 1.36 (0.96 to 1.92) | 0.082 |
| 2–5 years | 1.47 (1.08 to 2.01) | 0.015* | 1.48 (1.08 to 2.02) | 0.014* |
| 6–11 years | 0.95 (0.67 to 1.34) | 0.754 | 0.98 (0.69 to 1.39) | 0.906 |
| 12–18 years | 1.40 (0.77 to 2.54) | 0.271 | 1.41 (0.76 to 2.61) | 0.279 |
| Sex | ||||
| Female | Ref | Ref | ||
| Male | 0.93 (0.75 to 1.15) | 0.504 | 0.92 (0.74 to 1.14) | 0.433 |
| Ambiguous | Non-estimable | Non-estimable | ||
| Rank of prescriber | ||||
| House officer | Ref | Ref | ||
| Specialised nurse | 1.34 (0.87 to 2.05) | 0.185 | 1.30 (0.82 to 2.04) | 0.264 |
| Physician assistant | 0.88 (0.61 to 1.26) | 0.476 | 0.86 (0.60 to 1.24) | 0.417 |
| Medical officer | 1.45 (1.13 to 1.86) | 0.004* | 1.45 (1.12 to 1.86) | 0.004* |
| Resident | 1.32 (0.59 to 2.95) | 0.506 | 1.31 (0.58 to 2.99) | 0.514 |
| Specialist (paediatricians) | 1.98 (0.46 to 8.52) 0.361 | 2.19 (0.52 to 9.13) 0.283 | ||
| History of fever | ||||
| No | Ref | Ref | ||
| Yes | 1.31 (1.04 to 1.65) | 0.025* | 1.28 (1.01 to 1.62) | 0.044* |
| Information not available | 0.96 (0.62 to 1.50) | 0.866 | 0.89 (0.57 to 1.39) | 0.613 |
| Prior antibiotics given | ||||
| No | Ref | Ref | ||
| Yes | 0.78 (0.56 to 1.07) | 0.126 | 0.80 (0.58 to 1.11) | 0.188 |
| Information not available | 0.98 (0.77 to 1.24) | 0.844 | 1.01 (0.78 to 1.29) | 0.965 |
*
P value <0.05. Analysis was restricted to prescriptions with an appropriate indication and antibiotic choice.
aOR, adjusted OR.