Table 2.
Pretreatment host-state markers by MPR status (full cohort, n=738).
| Marker | Domain | MPR (n=302) | Non-MPR (n=436) | P |
|---|---|---|---|---|
| Cortisol, µg/dL | Endocrine | 11.88 (10.54-13.17) | 14.57 (13.10-15.93) | <0.001 |
| FT3, pmol/L | Endocrine | 4.64 (4.44-4.88) | 4.28 (4.03-4.48) | <0.001 |
| Albumin, g/L | Nutrition | 42.20 (40.80-43.70) | 39.20 (37.60-40.73) | <0.001 |
| Prealbumin, mg/L | Nutrition | 261 (241-284) | 216 (194-240) | <0.001 |
| PNI | Nutrition | 51.18 (48.85-53.19) | 46.23 (43.69-48.54) | <0.001 |
| Vitamin D, ng/mL | Micronutrient | 26.35 (23.30-29.08) | 20.50 (17.80-23.50) | <0.001 |
| Lymphocyte, 109/L | Inflammation | 1.75 (1.59-1.93) | 1.42 (1.23-1.59) | <0.001 |
| Neutrophil, 109/L | Inflammation | 3.47 (3.13-3.91) | 4.16 (3.79-4.59) | <0.001 |
| CRP, mg/L | Inflammation | 3.09 (2.20-4.47) | 6.96 (4.73-10.30) | <0.001 |
| NLR | Inflammation | 1.94 (1.67-2.38) | 2.92 (2.39-3.70) | <0.001 |
| SII | Inflammation | 432 (347-577) | 734 (548-983) | <0.001 |
| CAR | Inflammation | 0.07 (0.05-0.11) | 0.18 (0.12-0.28) | <0.001 |
| ENI-Score | Score | 64.55 (40.17-80.40) | 17.45 (6.92-35.60) | <0.001 |
Values are median (IQR); P values are from Mann–Whitney U tests. The direction of every difference was consistent across all three cohorts. FT3, free triiodothyronine; SII, systemic immune-inflammation index; other abbreviations as in Table 1.