Table 4.
Univariable and multivariable logistic regression for MPR (n=738).
| Variable | Univariable OR (95% CI) | P | Multivariable OR (95% CI) | P |
|---|---|---|---|---|
| ENI-Score (per 10 points) | 1.67 (1.56-1.80) | <0.001 | 1.72 (1.59-1.86) | <0.001 |
| Age (per year) | 0.99 (0.97-1.00) | 0.142 | 1.00 (0.98-1.02) | 0.821 |
| Male sex | 0.77 (0.56-1.05) | 0.096 | 0.83 (0.56-1.25) | 0.373 |
| ECOG PS ≥1 | 0.69 (0.51-0.93) | 0.016 | 0.72 (0.49-1.07) | 0.101 |
| Clinical T4 | 0.57 (0.42-0.76) | <0.001 | 0.52 (0.35-0.77) | <0.001 |
| Clinical N2/N3 | 0.64 (0.48-0.87) | 0.004 | 0.62 (0.42-0.92) | 0.017 |
| EGJ origin | 1.09 (0.71-1.68) | 0.703 | 1.32 (0.75-2.31) | 0.338 |
| PD-L1 CPS ≥5 | 1.77 (1.31-2.41) | <0.001 | 2.15 (1.44-3.21) | <0.001 |
| dMMR/MSI-H | 3.14 (1.75-5.65) | <0.001 | 3.70 (1.79-7.65) | <0.001 |
| XELOX vs SOX | 1.06 (0.76-1.48) | 0.716 | 1.85 (1.15-2.98) | 0.011 |
| FLOT vs SOX | 1.19 (0.80-1.77) | 0.394 | 1.28 (0.76-2.16) | 0.358 |
| DOS vs SOX | 1.14 (0.66-1.97) | 0.641 | 1.26 (0.61-2.61) | 0.531 |
OR, odds ratio; CI, confidence interval. The multivariable model mutually adjusts for all listed variables; the ENI-Score, PD-L1 CPS ≥5, and dMMR/MSI-H remain independent predictors. Abbreviations as in Table 1.