Table 2.
Baseline characteristics and early neurological outcome after 1:1 propensity score matching.
| Characteristic | Argatroban (n = 50) | Control (n = 50) | p value |
|---|---|---|---|
| Age (years), mean (SD) | 69.50 (10.56) | 69.58 (12.01) | 0.972 |
| Male, n (%) | 31 (62.0%) | 36 (72.0%) | 0.395 |
| Admission SBP (mmHg), mean (SD) | 158.60 (19.01) | 158.90 (16.54) | 0.933 |
| Admission NIHSS score, median [IQR] | 3.00 [2.00, 5.00] | 3.50 [2.00, 4.00] | 0.823 |
| Fazekas grade, median [IQR] | 1.00 [1.00, 2.00] | 1.00 [1.00, 2.00] | 0.876 |
| Early neurological deterioration, n (%) | 1 (2.0%) | 12 (24.0%) | 0.002 |
SBP, systolic blood pressure; NIHSS, National Institutes of Health Stroke Scale; SD, standard deviation; IQR, interquartile range. Early neurological deterioration was defined as an increase of ≥4 points in the NIHSS score at 72 h compared to admission. p values were calculated using the independent t-test, Mann–Whitney U test, Chi-square test, or Fisher’s exact test, as appropriate.